L-Carnosine and Autism

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“I want to ride in your car!”  Declan looked pleadingly at his dad.

“But Declan, your car seat is in mommy’s car.  You must ride with mommy in her car.”

“But, you could pick my seat up and take it out of mommy’s car and put it in your car.”



That moment when you realize your child with special needs just did something you never thought they would be able to do.

My husband and I look at each other with our eyes wide.  We picked Declan up and began to cheer.  Does he have any idea what he just said?  We knew what he did!

Declan solved a problem.  He provided a solution.  It was a solution that involved steps.  In the past, he would have started running in circles and swaying his head.  Or worse, sat there and screamed.  That is his baseline.

This time?  He provided a complex solution to a problem.


We are in the process of trying out a new supplement, L-Carnosine.  I read an article in Autism Parenting Magazine (found here) the discussed possible benefits of L-Carnosine for children with autism.

I followed up with some more online research.  I found an article on Nutrition Review (found here) that talked about L-Carnosine and autism.

In the article, I learned that L-Carnosine is a naturally occurring amino acid found in the muscle, heart and brain tissue.

L-Carnosine inhibits the formation of carbonyl groups, thereby reducing the formation of abnormal proteins.

L-Carnosine is already used to treat liver disease, cataracts, Alzheimer’s disease and cancer.

Recently, L-Carnosine has shown the potential to help children with Autism Spectrum Disorder with language and behavior.

In a study, researchers provided 31 children with autism 400 mg of L=Carnosine for 8 weeks.  The results of their study found improvements in:

  • Behavior
  • Socialization
  • Communication
  • Increase in Language Comprehension
  • Vocabulary
  • Biweekly Parent Reports

Chez et al, report L-Carnosine to benefit people with autism in the following ways:

  • Improved Language
  • Auditory Processing
  • Socialization
  • Awareness of Surroundings
  • Fine Motor Planning
  • Expressive Language


L-Carnosine is non-toxic and a safe substance.  It can be taken with or without food.  Per Dr. Chez, the recommended dosage is 400 mg twice a day.

Manic or hyperactive patients may have an increase in hyperactive behavior and may experience insomnia.  If this happens, Dr. Chez recommends decreasing the dosage.

If a person stops taking the L-Carnosine, there could be a regression in gained behavior.  Function was regained when the L-Carnosine was started again.

Since 2001, Dr. Chez has been studying the effects of L-Carnosine on children with autism.  There have been no negative physical changes noted.

Yes.  Based on the research, I was willing to try L-Carnosine.

I started with the recommended dosage of 400 mg.  I put Declan’s supplements in a juice cup with apple juice.  After a week, Declan was back to where he was at 2 years of age:  All over the place.  Nothing held his attention for more than a few minutes.  He was into everything.  He was breaking things, including furniture.  The screaming!  He screamed about everything.  And yes, we had more sleepless nights.

So, I decreased the dosage.  The erratic behavior began to decrease.  The screaming lessened.

And clearer statements are being made.  There is more thought happening!  Complex, problem solving thoughts!  Really exciting developments.


I need to point out I am not a Doctor.  If you are considering starting a new supplement talk it over with your Physician.

I personally made the choice to give the supplement to Declan based on articles and research I have read.

It is in my opinion we have had success with the supplement.  I will continue to use it.  I am very excited for Declan!




7 thoughts on “L-Carnosine and Autism

  1. Congradulations on your discovery! Will have to send a copy of this post to my mom, maybe my little brother could benefit from getting a dose of the supplement.

    Again you prove that doctor’s do not necessarily know everything. I learned that long ago by experimenting on my own body. Where is the cheapest place to purchase this supplement?

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